Vitamin D deficiency in pediatric critical illness
نویسندگان
چکیده
منابع مشابه
The association of vitamin D status with pediatric critical illness.
OBJECTIVES Vitamin D is a pleiotropic hormone important for the proper functioning of multiple organ systems. It has been hypothesized that vitamin D deficiency could contribute to or worsen outcomes in critical illness. The study objective was to determine the prevalence of vitamin D deficiency, risk factors for its presence, and potential association with clinically relevant outcomes in criti...
متن کاملVitamin D deficiency and stroke
Vitamin D comprises a group of fat-soluble pro-hormones, obtained from sun exposure, food, and supplements, and it must undergo two hydroxylation reactions to be activated in the body. Several studies have shown the role of vitamin D in mineral metabolism regulation, especially calcium, phosphorus, and bone metabolism. Some factors such as inadequate vitamin intake and liver or kidney disorders...
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BACKGROUND Metabolic homeostasis is substantially disrupted in critical illness. Given the pleiotropic effects of vitamin D, we hypothesized that metabolic profiles differ between critically ill patients relative to their vitamin D status. METHODS We performed a metabolomics study on biorepository samples collected from a single academic medical center on 65 adults with systemic inflammatory ...
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Methods We performed a prospective observational cohort of MICU patients at the Brigham and Women’s Hospital from 2008-2010 [n=49]. The exposure of interest was 25(OH)D categorized a priori as deficiency (25(OH)D ≤ 15 ng/mL) and measured via competitive chemiluminescence immunoassay. Circulating plasma mitochondrial DNA (mt-DNA) were assessed by measuring copy number of the NADH dehydrogenase 1...
متن کاملVitamin D Deficiency in Pediatric Fracture Patients: Prevalence, Risk Factors, and Vitamin D Supplementation
OBJECTIVE Although vitamin D levels are not routinely monitored in pediatric fracture patients, identification of children with a vitamin D deficiency may be clinically relevant because of the potential role of vitamin D in fracture healing. This study aimed to determine the prevalence of vitamin D deficiency in a pediatric fracture population and to identify risk factors for deficiency. METH...
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ژورنال
عنوان ژورنال: Journal of Clinical & Translational Endocrinology
سال: 2014
ISSN: 2214-6237
DOI: 10.1016/j.jcte.2014.09.002